Expert Viral vector production (H/F)

Expert Viral vector production (H/F)

Cellectis is a clinical-stage biopharmaceutical company focused on developing a new generation of cancer immunotherapies based on gene-edited T-cells (UCART). By capitalizing on its 18 years of expertise in gene editing – built on its flagship TALEN® technology and pioneering electroporation system PulseAgile – Cellectis uses the power of the immune system to target and eradicate cancer cells.

Using its life-science-focused, pioneering genome engineering technologies, Cellectis’ goal is to create innovative products in multiple fields and with various target markets.

Cellectis is listed on the Nasdaq market (ticker: CLLS) and on the NYSE Alternext market (ticker: ALCLS). To find out more about us, visit our website: www.cellectis.com

Job Summary

We are seeking a highly motivated individual to join us as an expert for the production of GMP batches viral vectors.  The successful candidate will work within the manufacturing team to:

  • Finalize the development of proprietary, GMP-compatible AAV/rLV processes and related analytics, contribute to design, construction and qualification of the Cellectis internal GMP facility,
  • Overview process and analytical transfer to Cellectis GMP facility and/or CMOs,
  • Supervise GMP production of high quality batches to support clinical development
  • Implement process improvement program to raise clinical processes to commercial level,

Skills requirements

  • Strong scientific mindset with ability to understand and adapt to production constraints
  • Be creative and pragmatic as well as efficient solution-finder
  • Be a team player and efficiently work individually
  • Comfortable in a fast-paced small company environment and able to multi-task and adjust workload based upon changing priorities
  • Ability to interact with internal and external partners
  • Possess management skills

Education Requirements

  • PhD in virology or equivalent with deep knowledge of viral vector biology
  • Hands-on experience and troubleshooting proficiency for production of AAV/rLV up to pilot scale including cell culture, purification and formulation.
  • Knowledge of viral vector analytics
  • Knowledge of GMP
  • Excellent written and oral communication skills in English (French would be a plus)

Localisation

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